Story by Carlos A Madera P, M.Sc, Ph.D, Universidad del Valle, Cali-Colombia; Daniel Ascuntar R, M.Sc, DAGMA, Cali-Colombia. — The Cañaveralejo, Meléndez and Lili river basin. Cali is Colombia’s second-largest city and third most populous after Bogota and Medellin. As the only major Colombian city with access to the Pacific Coast, Cali is the main urban center in the south and has one of Colombia’s fastest-growing economies.